Lactose intolerance

• Limited capacity or inability to digest milk sugar (lactose).

 Often mistaken for or mixed with cows milk protein intolerance (which is an allergy to protein(s) in cows milk).

  Is most commonly due to post-viral gastroenteritis lactase deficiency, e.g. rotavirus. Most cases are transient and short lasting (<4–6wks).

 In older healthy children and adults, lactase levels commonly decline with subsequent variable severity intolerance (especially in certain populations, e.g. South-east Asian and Afro-Caribbean).

 Rarely due to genetic congenital lactase deficiency (primary). Infants present with severe diarrhoea after lactose exposure.